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EntityQ422322· pop 15· linked from 598 articles

Also known as 4-chloro-17β-hydroxyandrost-4-en-3-one

Clostebol (; also known as 4-chlorotestosterone) is a synthetic anabolic–androgenic steroid (AAS). Clostebol is the 4-chloro derivative of the natural hormone testosterone. The chlorination prevents conversion to dihydrotestosterone (DHT) while also rendering the chemical incapable of conversion to estrogen. Although usually used as an ester including clostebol acetate (Macrobin, Steranabol, Alfa-Trofodermin, Megagrisevit), clostebol caproate (Macrobin-Depot), or clostebol propionate (Yonchlon), unmodified/non-esterified clostebol is also reported to be marketed, under the brand name Trofoderm

Wikidata facts

Mass
322.17
Show 5 more facts
chemical formula
C₁₉H₂₇ClO₂
canonical SMILES
CC12CCC3C(C1CCC2O)CCC4=C(C(=O)CCC34C)Cl
Commons category
Clostebol
isomeric SMILES
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=C(C(=O)CC[C@]34C)Cl
World Health Organisation international non-proprietary name
clostebol
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Article

9 sections
Contents
  • Medical uses
  • Side effects
  • Chemistry
  • Society and culture
  • Nutritional supplements
  • Publicized abuse or contamination cases
  • Regulation
  • See also
  • References

Clostebol (; also known as 4-chlorotestosterone) is a synthetic anabolic–androgenic steroid (AAS). Clostebol is the 4-chloro derivative of the natural hormone testosterone. The chlorination prevents conversion to dihydrotestosterone (DHT) while also rendering the chemical incapable of conversion to estrogen. Although usually used as an ester including clostebol acetate (Macrobin, Steranabol, Alfa-Trofodermin, Megagrisevit), clostebol caproate (Macrobin-Depot), or clostebol propionate (Yonchlon), unmodified/non-esterified clostebol is also reported to be marketed, under the brand name Trofodermin-S in Mexico.

Clostebol is a weak AAS with potential use as a performance enhancing drug. It is currently banned by the World Anti-Doping Agency. Chlorodehydromethyltestosterone (Oral Turinabol), combining the chemical structures of clostebol and metandienone, was widely used in the East German state-sponsored doping program.

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