CRISP1
Sign in to saveAlso known as ARP, AEGL1, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP, HEL-S-57, cysteine rich secretory protein 1
Cysteine-rich secretory protein 1 is a cysteine-rich secretory protein that in humans is encoded by the CRISP1 gene.
In the Vinony graph
Vinony's link graph records 2 inbound references to CRISP1, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 6.
Vinony links it to 5 Wikipedia language editions.
Gene data
CRISP1- Name
- cysteine rich secretory protein 1
- Type
- protein-coding
- Position
- 49,834,257–49,877,096 (−)
- Aliases
- AEGL1, ARP, CRISP-1, HEL-S-57, HSCRISP1D, HSCRISP1G, HUMARP
- Ensembl
- ENSG00000124812
- RefSeq RNA
- NM_001131.3, NM_001205220.2, NM_170609.2, XM_011514315.4, XM_017010320.3
- RefSeq protein
- NP_001122.2, NP_001192149.1, NP_733758.1, XP_011512617.1, XP_016865809.1
Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head, where it plays a role in sperm-egg fusion. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
cysteine rich secretory protein 1
- Symbol
- CRISP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:49,834,257-49,877,096
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 81683
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/167
- genomic start
- 49801970
- chromosome
- human chromosome 6
- genomic end
- 49844809
- cytogenetic location
- 6p12.3
- expressed in
- head
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Cysteine-rich secretory protein 1 is a cysteine-rich secretory protein that in humans is encoded by the CRISP1 gene.
Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. This protein is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head where it plays a role at fertilization in sperm-egg fusion through complementary sites localized on the egg surface. Two isoforms are encoded by transcript variants of this gene.
Excerpted from Wikipedia’s “CRISP1” article, available under the CC BY-SA 4.0 licence.