Also known as DULLARD, HSA011916, NET56, CTD nuclear envelope phosphatase 1
In cell biology, CTDNEP1 (CTD nuclear envelope phosphatase 1) is a protein coding gene involved in neural development. It is a member of DXDX(T/V) phosphatase family and is a potential regulator of neural tube development in Xenopus. The gene promotes neural development by inhibiting bone morphogenetic proteins (BMPs). The encoded protein is relatively small and only contains 244 amino acids.
Enables protein serine/threonine phosphatase activity. Involved in several processes, including positive regulation of triglyceride biosynthetic process; protein dephosphorylation; and protein localization to nucleus. Located in endoplasmic reticulum membrane; lipid droplet; and nuclear membrane. Part of Nem1-Spo7 phosphatase complex. [provided by Alliance of Genome Resources, Apr 2022]
Biological process
In cell biology, CTDNEP1 (CTD nuclear envelope phosphatase 1) is a protein coding gene involved in neural development. It is a member of DXDX(T/V) phosphatase family and is a potential regulator of neural tube development in Xenopus. The gene promotes neural development by inhibiting bone morphogenetic proteins (BMPs). The encoded protein is relatively small and only contains 244 amino acids.
== Description == CTDnep1, which stands for CTD nuclear envelope phosphatase 1. It is a protein coding gene, which include phosphatase activity and protein serine/threonine phosphatase activity. CTDnep1 encodes a protein serine/threonine phosphatase and dephosphorylates LPIN1 and LPIN2. LPIN1 and LPIN2 catalyze the reaction of the conversion of phosphatidic acid to diacylglycerol. The reaction can affect and change the lipid concentration of the endoplasmic reticulum and the nucleus.
via MyGene.info
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).