Also known as CW-1, TCTEL1, tctex-1, dynein light chain Tctex-type 1, TCTEX1
Dynein light chain Tctex-type 1 is a protein that in humans is encoded by the DYNLT1 gene.
This gene encodes a component of the motor complex, cytoplasmic dynein, which transports cellular cargo along microtubules in the cell. The encoded protein regulates the length of primary cilia which are sensory organelles found on the surface of cells. The protein encoded by this gene interacts with viral proteins, like the minor capsid protein L2 of human papillomavirus, and is required for dynein-mediated delivery of the viral nucleic acid to the host nucleus. This protein interacts with oncogenic nucleoporins to disrupt gene regulation and cause leukemic transformation. Pseudogenes of this gene are present on chromosomes 4 and 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014].
via MyGene.info
Dynein light chain Tctex-type 1 is a protein that in humans is encoded by the DYNLT1 gene.
Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. TCTEX1 is a dynein light chain involved in cargo binding (Chuang et al., 2005).[supplied by OMIM]
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).