DYNC1I2

Also known as DNCI2, IC2, DIC74, dynein cytoplasmic 1 intermediate chain 2, NEDMIBA

Cytoplasmic dynein 1 intermediate chain 2 is a protein that in humans is encoded by the DYNC1I2 gene.

Gene data

DYNC1I2

Name: dynein cytoplasmic 1 intermediate chain 2
Type: protein-coding
Position: 171,687,409–171,750,158 (+)
Aliases: DIC74, DNCI2, IC2, NEDMIBA
Ensembl: ENSG00000292102
RefSeq RNA: NM_001271785.2, NM_001271786.2, NM_001271787.2, NM_001271788.2, NM_001271789.2
RefSeq protein: NP_001258714.1, NP_001258715.1, NP_001258716.1, NP_001258717.1, NP_001258718.1

This gene encodes a member of the dynein intermediate chain family. The encoded protein is a non-catalytic component of the cytoplasmic dynein 1 complex, which acts as a retrograde microtubule motor to transport organelles and vesicles. A pseudogene of this gene is located on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012].