DYNLRB1

Also known as BITH, BLP, DNCL2A, DNLC2A, ROBLD1, dynein light chain roadblock-type 1

Dynein light chain roadblock-type 1 is a protein that in humans is encoded by the DYNLRB1 gene.

Gene data

DYNLRB1

Name: dynein light chain roadblock-type 1
Type: protein-coding
Aliases: BITH, BLP, DNCL2A, DNLC2A, ROBLD1

This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013].

via MyGene.info

Wikidata facts

Image: Protein DYNLRB1 PDB 1y4o.png

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Dynein light chain roadblock-type 1 is a protein that in humans is encoded by the DYNLRB1 gene.

This gene is a member of the roadblock dynein light chain family and encodes a cytoplasmic protein that is capable of binding intermediate chain proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression.