CNBP

Also known as CNBP1, DM2, PROMM, RNF163, ZCCHC22, ZNF9, CCHC-type zinc finger nucleic acid binding protein

Cellular nucleic acid-binding protein is a protein that in humans is encoded by the CNBP gene.

Gene data

CNBP

Name: CCHC-type zinc finger nucleic acid binding protein
Type: protein-coding
Position: 129,167,818–129,184,008 (−)
Aliases: CNBP1, DM2, PROMM, RNF163, ZCCHC22, ZNF9
Ensembl: ENSG00000169714
RefSeq RNA: NM_001127192.2, NM_001127193.2, NM_001127194.2, NM_001127195.2, NM_001127196.2
RefSeq protein: NP_001120664.1, NP_001120665.1, NP_001120666.1, NP_001120667.1, NP_001120668.1

This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion from <30 repeats to 75-11000 repeats in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016].