CEBPB
Sign in to saveAlso known as C/EBP-beta, IL6DBP, NF-IL6, TCF5, CCAAT/enhancer binding protein beta, CCAAT enhancer binding protein beta
CCAAT/enhancer-binding protein beta is a protein that in humans is encoded by the CEBPB gene.
Gene data
CEBPB- Name
- CCAAT enhancer binding protein beta
- Type
- protein-coding
- Position
- 50,190,734–50,192,690 (+)
- Aliases
- C/EBP-beta, IL6DBP, NF-IL6, TCF5
- Ensembl
- ENSG00000172216
- RefSeq RNA
- NM_001285878.1, NM_001285879.1, NM_005194.4
- RefSeq protein
- NP_001272807.1, NP_001272808.1, NP_005185.2
This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions. [provided by RefSeq, Oct 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
CCAAT enhancer binding protein beta
- Symbol
- CEBPB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:50,190,734-50,192,690
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- 1gtw.png
Show 5 more facts
- HomoloGene ID
- 3807
- exact match
- identifiers.org/ncbigene/1051
- genomic end
- 50192668
- genomic start
- 50190830
- cytogenetic location
- 20q13.13
Sources (4)
via Wikidata · CC0
~5 min read
Article
8 sectionsContents
- Function
- Target genes
- Enhancer Binding-Protein
- Cancer
- Interactions
- See also
- References
- External links
CCAAT/enhancer-binding protein beta is a protein that in humans is encoded by the CEBPB gene.
== Function ==