CYP3A5

Name

cytochrome P450 family 3 subfamily A member 5

Type

protein-coding

Position

99,647,442–99,680,043 (−)

Aliases

CP35, CYPIIIA5, P450PCN3, PCN3

Ensembl

ENSG00000106258

RefSeq RNA

NM_000777.5, NM_001190484.3, NM_001291829.2, NM_001291830.2, NR_033807.3

RefSeq protein

NP_000768.1, NP_001177413.1, NP_001278758.1, NP_001278759.1

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014].

via MyGene.info

Gene · Ensembl

cytochrome P450 family 3 subfamily A member 5

Symbol

CYP3A5

Biotype

Protein coding

Organism

Homo sapiens

Location

7:99,647,442-99,680,043

Strand

Reverse (−)

Assembly

GRCh38