DDX5

Name

DEAD-box helicase 5

Type

protein-coding

Position

64,498,253–64,508,199 (−)

Aliases

G17P1, HLR1, HUMP68, p68

Ensembl

ENSG00000108654

RefSeq RNA

NM_001320595.2, NM_001320596.3, NM_001320597.2, NM_004396.5, XM_047435513.1

RefSeq protein

NP_001307524.1, NP_001307525.1, NP_001307526.1, NP_004387.1, XP_047291469.1

This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2017].

via MyGene.info

Gene · Ensembl

DEAD-box helicase 5

Symbol

DDX5

Biotype

Protein coding

Organism

Homo sapiens

Location

17:64,498,253-64,508,199

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

DEAD BOX 5.png

via Wikidata · CC0