Also known as FIB, FLRN, RNU3IP1, fibrillarin, Nop1
'''rRNA 2'-O-methyltransferase fibrillarin' is an enzyme that in humans is encoded by the FBL'' gene.
Gene data
FBL- Name
- fibrillarin rRNA 2'-O-methyltransferase
- Type
- protein-coding
- Aliases
- FIB, FLRN, Nop1, RNU3IP1
This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
fibrillarin
- Symbol
- FBL
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:39,834,443-39,846,440
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein FBL PDB 2ipx.png
Show 5 more facts
- HomoloGene ID
- 1099
- exact match
- identifiers.org/ncbigene/2091
- genomic start
- 40325098
- genomic end
- 39846379
- cytogenetic location
- 19q13.2
via Wikidata · CC0
~3 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
'''rRNA 2'-O-methyltransferase fibrillarin' is an enzyme that in humans is encoded by the FBL'' gene.
== Function ==