denopamine
Sign in to saveAlso known as (R)-(-)-denopamine, 4-[(1R)-2-[2-(3,4-dimethoxyphenyl)ethylamino]-1-hydroxyethyl]phenol
Denopamine (INN) is a drug which acts as a β1 adrenergic receptor agonist. It is used in the treatment of angina and may also have potential uses in the treatment of congestive heart failure and for clearing pulmonary edema. It is marketed in Japan under the brand name Kalgut and available as tablets of 5 and 10 mg, and 5% fine granules.
Research
151 papers- Denopamine, a selective beta1-receptor agonist and a new coronary vasodilator.Current medical research and opinion · 2002
- Denopamine, a beta1-adrenergic agonist, prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-alpha production in the heart.Journal of the American College of Cardiology · 1998
- Denopamine, a beta(1)-adrenergic agonist, increases alveolar fluid clearance in ex vivo rat and guinea pig lungs.Journal of applied physiology (Bethesda, Md. : 1985) · 2001
- [Denopamine responsive pulmonary hypertension in a patient with collagen disease].Ryumachi. [Rheumatism] · 1989
- Regioselective glucuronidation of denopamine: marked species differences and identification of human udp-glucuronosyltransferase isoform.Drug metabolism and disposition: the biological fate of chemicals · 2005
via PubMed
Wikidata facts
- Mass
- 317.162708
Show 4 more facts
- chemical formula
- C₁₈H₂₃NO₄
- canonical SMILES
- COC1=C(C=C(C=C1)CCNCC(C2=CC=C(C=C2)O)O)OC
- isomeric SMILES
- COC1=C(C=C(C=C1)CCNC[C@@H](C2=CC=C(C=C2)O)O)OC
- Commons category
- Denopamine
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Article
1 sectionsContents
- References
Denopamine (INN) is a drug which acts as a β1 adrenergic receptor agonist. It is used in the treatment of angina and may also have potential uses in the treatment of congestive heart failure and for clearing pulmonary edema. It is marketed in Japan under the brand name Kalgut and available as tablets of 5 and 10 mg, and 5% fine granules.
== References ==