Structure via PubChem · Public domain (PubChem)
eledoisin
Sign in to saveAlso known as ELD 950, ELD-950, eledone peptide
Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of neuropeptides.
In the Vinony graph
Vinony's link graph records 164 inbound references to eledoisin, and connects out to orexin, neuropeptide and tachykinins.
It is catalogued under topics including Hendecapeptides, Marine neurotoxins and Neuropeptides.
Vinony links it to 8 Wikipedia language editions.
Chemical data
- Formula
- C54H85N13O15S
- Molecular weight
- 1188.4 g/mol
- IUPAC name
- (3S)-3-[[(2S)-6-amino-2-[[(2S)-3-hydroxy-2-[[(2S)-1-[(2S)-5-oxopyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
- SMILES
- CC[C@H](C)[C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCC(=O)N3
- InChIKey
- AYLPVIWBPZMVSH-FCKMLYJASA-N
- XLogP
- -3.6
- Polar surface area
- 463 Ų
- H-bond donors
- 14
- H-bond acceptors
- 17
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Protein
via ChEMBL · EBI
Research
717 papers- Hypotensive peptides: bradykinin, kallidin, and eledoisin.Advances in pharmacology · 1966
- [ELEDOISIN. CHEMISTRY, PHARMACOLOGY CLINICO-EXPERIMENTAL AND PRELIMINARY THERAPEUTICAL EXPERIENCES].Deutsche medizinische Wochenschrift (1946) · 1965
- Synthesis of eledoisin.Experientia · 1962
- Renal prostaglandins.Advances in prostaglandin and thromboxane research · 1976
- Eledoisin and lacrimal secretion in the rabbit.Current eye research · 1990
via PubMed
Wikidata facts
- Subclass of
- tachykinins
- Mass
- 1187.60088
Show 5 more facts
- chemical formula
- C₅₄H₈₅N₁₃O₁₅S
- isomeric SMILES
- CC[C@H](C)[C@@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCC(=O)N3
- canonical SMILES
- CCC(C)C(C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC1=CC=CC=C1)NC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C2CCCN2C(=O)C3CCC(=O)N3
- subject has role
- neurotransmitter
- Commons category
- Eledoisin
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
1 sectionsContents
- References
Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of neuropeptides.
It was first isolated from the posterior salivary glands of two mollusk species Eledone muschata and Eledone aldovandi, which belong to the octopod order of Cephalopoda.
Excerpted from Wikipedia’s “eledoisin” article, available under the CC BY-SA 4.0 licence.