emodin
Sign in to saveAlso known as 1,3,8-Trihydroxy-6-methylanthraquinone, 1,3,8-trihydroxy-6-methyl-9,10-anthracenedione, Schuttgelb, 1,3,8-trihydroxy-6-methyl-9,10-anthraquinone, Frangula emodin, Emodol, Frangulinic acid
Emodin (6-methyl-1,3,8-trihydroxyanthraquinone) is an organic compound. Classified as an anthraquinone, it can be isolated from rhubarb, buckthorn, and Japanese knotweed (Reynoutria japonica syn. Polygonum cuspidatum). Emodin is particularly abundant in the roots of the Chinese rhubarb (Rheum palmatum), knotweed and knotgrass (Polygonum cuspidatum and Polygonum multiflorum) as well as Hawaii 'au'auko'i cassia seeds or coffee weed (Semen cassia). It is specifically isolated from Rheum palmatum L. It is also produced by many species of fungi, including members of the genera Aspergillus, Pyrenoch
Research
3,899 papers- Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics.Phytotherapy research : PTR · 2016
- Emodin induces ferroptosis in colorectal cancer through NCOA4-mediated ferritinophagy and NF-κb pathway inactivation.Apoptosis : an international journal on programmed cell death · 2024
- Emodin Inhibits NLRP3 Inflammasome Activation and Protects Against Sepsis via Promoting FUNDC1-Mediated Mitophagy.International journal of biological sciences · 2025
- Emodin - A natural anthraquinone derivative with diverse pharmacological activities.Phytochemistry · 2021
- Emodin: A metabolite that exhibits anti-neoplastic activities by modulating multiple oncogenic targets.Toxicology in vitro : an international journal published in association with BIBRA · 2021
via PubMed
Wikidata facts
- Mass
- 270.053
Show 2 more facts
- chemical formula
- C₁₅H₁₀O₅
- canonical SMILES
- CC1=CC(=C2C(=C1)C(=O)C3=CC(=CC(=C3C2=O)O)O)O
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Article
4 sectionsContents
- Pharmacology
- List of species
- Compendial status
- References
Emodin (6-methyl-1,3,8-trihydroxyanthraquinone) is an organic compound. Classified as an anthraquinone, it can be isolated from rhubarb, buckthorn, and Japanese knotweed (Reynoutria japonica syn. Polygonum cuspidatum). Emodin is particularly abundant in the roots of the Chinese rhubarb (Rheum palmatum), knotweed and knotgrass (Polygonum cuspidatum and Polygonum multiflorum) as well as Hawaii 'au'auko'i cassia seeds or coffee weed (Semen cassia). It is specifically isolated from Rheum palmatum L. It is also produced by many species of fungi, including members of the genera Aspergillus, Pyrenochaeta, and Pestalotiopsis, inter alia. The common name is derived from Rheum emodi, a taxonomic synonym of Rheum australe (Himalayan rhubarb), and synonyms include emodol, frangula emodin, rheum emodin, 3-methyl-1,6,8-trihydroxyanthraquinone, Schüttgelb (Schuttgelb), and Persian Berry Lake.
==Pharmacology== Emodin is an active component of several plants used in traditional Chinese medicine (TCM) such as Rheum palmatum, Polygonum cuspidatum, and Polygonum multiflorum. It has various actions including laxative, anticancer, antibacterial and antiinflammatory effects, and has also been identified as having potential antiviral activity against coronaviruses such as SARS-CoV-2, being one of the major active components of the antiviral TCM formulation Lianhua Qingwen.