Enolase
Sign in to saveAlso known as IPR000941
Phosphopyruvate hydratase, usually known as enolase, is a metalloenzyme () that catalyses the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), the ninth and penultimate step of glycolysis. The chemical reaction is:
Key facts
- Enzyme.Name
- phosphopyruvate hydratase
- Enzyme.EC_number
- 4.2.1.11
- Enzyme.CAS_number
- 9014-08-8
- Enzyme.GO_code
- 0004634
- Enzyme.image
- Enolase 2ONE wpmp.png
- Enzyme.caption
- Yeast enolase dimer.
- Protein family.Symbol
- Enolase
- Protein family.Name
- Enolase
- Protein family.image
- 2XSX.pdb.png
- Protein family.caption
- Crystal structure of dimeric beta human enolase ENO3.
- Protein family.Pfam
- PF00113
- Protein family.Pfam_clan
- CL0227
- Protein family.InterPro
- IPR000941
- Protein family.PROSITE
- PDOC00148
- Protein family.SCOP
- 1els
via Wikipedia infobox
~9 min read
Encyclopedic overview
8 sectionsContents
- Isozymes
- Structure
- Mechanism
- Diagnostic uses
- Inhibitors
- References
- Further reading
- External links
Phosphopyruvate hydratase, usually known as enolase, is a metalloenzyme () that catalyses the conversion of 2-phosphoglycerate (2-PG) to phosphoenolpyruvate (PEP), the ninth and penultimate step of glycolysis. The chemical reaction is: 2-phospho-D-glycerate \rightleftharpoons phosphoenolpyruvate + H2O
Phosphopyruvate hydratase belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme is 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming).
Excerpted from Wikipedia’s “Enolase” article, available under the CC BY-SA 4.0 licence.