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ProteinQ21101155· pop 12· linked from 427 articles

Also known as 2-phospho-D-glycerate hydrolyase, neuron specific gamma enolase, gamma-enolase, 2-phospho-D-glycerate hydro-lyase, enolase 2 (gamma, neuronal), neurone-specific enolase, NSE, ENO2

mammalian protein found in Homo sapiens

In the Vinony graph

Vinony's link graph records 427 inbound references to Enolase 2, and connects out to neuron, PubMed and lymphoma.

Vinony files it under Diagnostic neurology, EC 4.2.1 and Genes on human chromosome 12.

Vinony links it to 12 Wikipedia language editions.

Protein · UniProt

Gamma-enolase

Gene
ENO2
Organism
Homo sapiens (Human)
Length
434 aa
Molecular mass
47,269 Da
Evidence
1: Evidence at protein level

Enolase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in glycolysis and the reverse reaction in gluconeogenesis (By similarity). Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity)

3D-structureAcetylationAlternative splicingCell membraneCytoplasmDirect protein sequencingGlycolysisHydroxylation
View on UniProt →

Swiss-Prot (reviewed) · via UniProt

Clinical Trials

29 registered

via ClinicalTrials.gov

Wikidata facts

Instance of
protein
Image
Protein ENO2 PDB 1te6.png
Show 3 more facts
biological process
glycolytic process
cell component
extracellular exosome
found in taxon
Homo sapiens
Sources (3)

via Wikidata · CC0

Connections

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