Structure via PubChem · Public domain (PubChem)
epicillin
Sign in to saveAlso known as Dexacillin, Dihydroampicillin
Epicillin (INN) is a penicillin antibiotic. It is not approved by the FDA for use in the United States.
In the Vinony graph
Vinony's link graph records 185 inbound references to epicillin, and connects out to antibiotic, ceftolozane/tazobactam and penicillin.
It is catalogued under topics including Chemical pages without DrugBank identifier, Drugboxes which contain changes to verified fields and Drugboxes which contain changes to watched fields.
Vinony links it to 8 Wikipedia language editions.
Chemical data
- Formula
- C16H21N3O4S
- Molecular weight
- 351.4 g/mol
- IUPAC name
- (2S,5R,6R)-6-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
- SMILES
- CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CCC=CC3)N)C(=O)O)C
- InChIKey
- RPBAFSBGYDKNRG-NJBDSQKTSA-N
- XLogP
- -1.3
- Polar surface area
- 138 Ų
- H-bond donors
- 3
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- bacterial disease
via ChEMBL · EBI
Research
73 papers- New antibiotics: epicillin, minocycline and spectinomycin a summary of their antibacterial activity, pharmacokinetic properties and therapeutic efficacy.Drugs · 1972
- Epicillin: experimental chemotherapy, pharmacodynamics, and susceptibility testing.Infection and immunity · 1971
- Epicillin: in vitro laboratory studies.Infection and immunity · 1971
- The value of epicillin and ampicillin in the treatment of meningococcal and pneumococcal meningitis.Scandinavian journal of infectious diseases · 1976
- Single oral dose of epicillin combined with probenecid in the treatment of gonorrhoea.Current medical research and opinion · 1980
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 351.125
Show 5 more facts
- chemical formula
- C₁₆H₂₁N₃O₄S
- canonical SMILES
- CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CCC=CC3)N)C(=O)O)C
- isomeric SMILES
- CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](C3=CCC=CC3)N)C(=O)O)C
- World Health Organisation international non-proprietary name
- epicillin
- subject has role
- antibiotic
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Epicillin (INN) is a penicillin antibiotic. It is not approved by the FDA for use in the United States.
It is an aminopenicillin.
Excerpted from Wikipedia’s “epicillin” article, available under the CC BY-SA 4.0 licence.
Available in 8 languages
via Wikidata sitelinks · CC0