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epitiostanol
Sign in to saveAlso known as 2,3-epithioandrostan-17-ol, Thiodrol, (1S,2S,4R,6S,8S,11R,12S,15S,16S)-2,16-dimethyl-5-thiapentacyclo[9.7.0.02,8.04,6.012,16]octadecan-15-ol, LSM-6713
Epitiostanol, sold under the brand name Thiodrol, is an injected antiestrogen and anabolic–androgenic steroid (AAS) of the dihydrotestosterone (DHT) group which was described in the literature in 1965 and has been marketed in Japan as an antineoplastic agent for the treatment of breast cancer since 1977.
Chemical data
- Formula
- C19H30OS
- Molecular weight
- 306.5 g/mol
- IUPAC name
- (1S,2S,4R,6S,8S,11R,12S,15S,16S)-2,16-dimethyl-5-thiapentacyclo[9.7.0.02,8.04,6.012,16]octadecan-15-ol
via PubChem
Wikidata facts
- Mass
- 306.20173658
Show 3 more facts
- isomeric SMILES
- C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CC[C@@H]4[C@@]3(C[C@@H]5[C@H](C4)S5)C
- chemical formula
- C₁₉H₃₀OS
- canonical SMILES
- CC12CCC3C(C1CCC2O)CCC4C3(CC5C(C4)S5)C
Sources (2)
via Wikidata · CC0
~3 min read
Encyclopedic overview
9 sectionsContents
- Medical uses
- Side effects
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- Society and culture
- Generic names
- References
Epitiostanol, sold under the brand name Thiodrol, is an injected antiestrogen and anabolic–androgenic steroid (AAS) of the dihydrotestosterone (DHT) group which was described in the literature in 1965 and has been marketed in Japan as an antineoplastic agent for the treatment of breast cancer since 1977.
==Medical uses== Epitiostanol is used as an antiestrogen and antineoplastic agent in the treatment of breast cancer. It has also been found to be effective in the treatment of gynecomastia.
Excerpted from Wikipedia’s “epitiostanol” article, available under the CC BY-SA 4.0 licence.