Also known as C8orf2, Erlin-2, NET32, SPFH2, SPG18, ER lipid raft associated 2
Erlin-2 is a protein that in humans is encoded by the ERLIN2 gene.
This gene encodes a member of the SPFH domain-containing family of lipid raft-associated proteins. The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1,4,5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors. Mutations in this gene are a cause of spastic paraplegia-18 (SPG18). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012].
via MyGene.info
Erlin-2 is a protein that in humans is encoded by the ERLIN2 gene.
== References ==
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).