AGO2
Sign in to saveAlso known as EIF2C2, Q10, argonaute 2, RISC catalytic component, PPD, CASC7, LINC00980, argonaute RISC catalytic component 2, LESKRES
Protein argonaute-2 is a protein that in humans is encoded by the EIF2C2 gene.
Gene data
AGO2- Name
- argonaute RISC catalytic component 2
- Type
- protein-coding
- Position
- 140,520,156–140,635,633 (−)
- Aliases
- CASC7, EIF2C2, LESKRES, LINC00980, PPD, Q10
- Ensembl
- ENSG00000123908
- RefSeq RNA
- NM_001164623.3, NM_012154.5, XM_011516965.3, XM_011516968.3, XM_047421695.1
- RefSeq protein
- NP_001158095.1, NP_036286.2, XP_011515267.1, XP_011515270.3, XP_047277651.1
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
argonaute RISC catalytic component 2
- Symbol
- AGO2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 8:140,520,156-140,635,695
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Estructura de la proteína AGO 2.jpg
Show 5 more facts
- HomoloGene ID
- 81825
- exact match
- identifiers.org/ncbigene/27161
- genomic end
- 140635633
- genomic start
- 141541264
- cytogenetic location
- 8q24.3
Sources (3)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Interactions
- References
- Further reading
Protein argonaute-2 is a protein that in humans is encoded by the EIF2C2 gene.
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with Dicer1 and play a role in short-interfering-RNA-mediated gene silencing.