ARL2

Also known as ARFL2, ADP ribosylation factor like GTPase 2, MRCS1

ADP-ribosylation factor-like protein 2 is a protein that in humans is encoded by the ARL2 gene.

In the Vinony graph

Within Vinony's link graph, ARL2 is referenced by 7 other articles, and connects out to PubMed, Ensembl genome database project and protein.

It is catalogued under the topic Genes on human chromosome 11.

Its subject is documented across 4 Wikipedia language editions.

Gene data

ARL2

Name: ARF like GTPase 2
Type: protein-coding
Position: 65,013,735–65,024,328 (+)
Aliases: ARFL2, MRCS1
Ensembl: ENSG00000213465
RefSeq RNA: NM_001199745.2, NM_001667.4
RefSeq protein: NP_001186674.1, NP_001658.2

This gene encodes a small GTP-binding protein of the RAS superfamily which functions as an ADP-ribosylation factor (ARF). The encoded protein is one of a functionally distinct group of ARF-like genes. [provided by RefSeq, Jul 2008].

Pathways

Signal Transduction Transport of small molecules Post-chaperonin tubulin folding pathway Protein folding Metabolism of proteins Transport of vitamins, nucleosides, and related molecules SLC-mediated transmembrane transport RAF/MAP kinase cascade MAPK family signaling cascades MAPK1/MAPK3 signaling

via MyGene.info

Gene · Ensembl

ARF like GTPase 2

Symbol: ARL2
Biotype: Protein coding
Organism: Homo sapiens
Location: 11:65,013,735-65,024,328
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein ARL2 PDB 1ksg.png

Show 7 more facts

HomoloGene ID: 1260
genomic end: 64789656
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/402
genomic start: 65014160
chromosome: human chromosome 11
cytogenetic location: 11q13.1

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

5 sections

Contents

Function
Interactions
References
External links
Further reading

ADP-ribosylation factor-like protein 2 is a protein that in humans is encoded by the ARL2 gene.

== Function == The ADP-ribosylation factor (ARF) genes are small GTP-binding proteins of the RAS superfamily. ARL2 is a member of a functionally distinct group of ARF-like genes. In photoreceptors, ARL2 participates in the trafficking of lipidated membrane-associated proteins. There is an evidence that increased activity of ARL2 protein is strongly correlated with increased mitochondria fusion, while loss of ARL2 activity results in a decreased rate of fusion.

Excerpted from Wikipedia’s “ARL2” article, available under the CC BY-SA 4.0 licence.