ARL2
Sign in to saveAlso known as ARFL2, ADP ribosylation factor like GTPase 2, MRCS1
ADP-ribosylation factor-like protein 2 is a protein that in humans is encoded by the ARL2 gene.
Gene data
ARL2- Name
- ARF like GTPase 2
- Type
- protein-coding
- Aliases
- ARFL2, MRCS1
This gene encodes a small GTP-binding protein of the RAS superfamily which functions as an ADP-ribosylation factor (ARF). The encoded protein is one of a functionally distinct group of ARF-like genes. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
ARF like GTPase 2
- Symbol
- ARL2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:65,013,735-65,024,328
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein ARL2 PDB 1ksg.png
Show 5 more facts
- HomoloGene ID
- 1260
- genomic end
- 64789656
- exact match
- identifiers.org/ncbigene/402
- genomic start
- 65014160
- cytogenetic location
- 11q13.1
Sources (4)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Interactions
- References
- External links
- Further reading
ADP-ribosylation factor-like protein 2 is a protein that in humans is encoded by the ARL2 gene.
== Function == The ADP-ribosylation factor (ARF) genes are small GTP-binding proteins of the RAS superfamily. ARL2 is a member of a functionally distinct group of ARF-like genes. In photoreceptors, ARL2 participates in the trafficking of lipidated membrane-associated proteins. There is an evidence that increased activity of ARL2 protein is strongly correlated with increased mitochondria fusion, while loss of ARL2 activity results in a decreased rate of fusion.