FABP2

Also known as FABPI, I-FABP, fatty acid binding protein 2

Fatty acid-binding protein 2 (FABP2), also known as Intestinal-type fatty acid-binding protein (I-FABP), is a protein that in humans is encoded by the FABP2 gene.

Gene data

FABP2

Name: fatty acid binding protein 2
Type: protein-coding
Position: 119,317,250–119,322,138 (−)
Aliases: FABPI, I-FABP
Ensembl: ENSG00000145384
RefSeq RNA: NM_000134.4
RefSeq protein: NP_000125.2

The protein encoded by this gene is an intracellular fatty acid-binding protein that participates in the uptake, intracellular metabolism, and transport of long-chain fatty acids. The encoded protein is also involved in the modulation of cell growth and proliferation. This protein binds saturated long-chain fatty acids with high affinity, and may act as a lipid sensor to maintain energy homeostasis. [provided by RefSeq, Aug 2017].

Pathways

PPAR signaling pathway - Homo sapiens (human)Fat digestion and absorption - Homo sapiens (human)Metabolism Triglyceride catabolism Metabolism of lipids Triglyceride metabolism PPAR signaling pathway Fatty acid transporters

via MyGene.info

Gene · Ensembl

fatty acid binding protein 2

Symbol: FABP2
Biotype: Protein coding
Organism: Homo sapiens
Location: 4:119,316,752-119,322,141
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein FABP2 PDB 1kzw.png

Show 6 more facts

HomoloGene ID: 107
genomic end: 120243545
genomic start: 119317250
Commons category: FABP2
exact match: identifiers.org/ncbigene/2169
cytogenetic location: 4q26

Sources (3)

via Wikidata · CC0

~1 min read

Article

4 sections

Contents

Function
Clinical significance
References
Further reading

Fatty acid-binding protein 2 (FABP2), also known as Intestinal-type fatty acid-binding protein (I-FABP), is a protein that in humans is encoded by the FABP2 gene.

== Function ==