FCRL4

Also known as CD307d, FCRH4, IGFP2, IRTA1, Fc receptor like 4

Fc receptor-like protein 4 is a protein that in humans is encoded by the FCRL4 gene. FCRL4 is an inhibitory receptor expressed on human memory B cells which resides in epithelial tissues.

In the Vinony graph

Within Vinony's link graph, FCRL4 is referenced by 6 other articles, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.

Vinony files it under Fc receptors and Genes on human chromosome 1.

Its subject is documented across 6 Wikipedia language editions.

Gene data

FCRL4

Name: Fc receptor like 4
Type: protein-coding
Position: 157,573,747–157,598,085 (−)
Aliases: CD307d, FCRH4, IGFP2, IRTA1
Ensembl: ENSG00000163518
RefSeq RNA: NM_031282.3, XM_011510034.2, XM_054338965.1
RefSeq protein: NP_112572.1, XP_011508336.1, XP_054194940.1

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009].

Gene Ontology

Biological process

immune response cell surface receptor signaling pathway

Molecular function

transmembrane signaling receptor activity protein binding

Cellular component

plasma membrane external side of plasma membrane cell surface cell surface

via MyGene.info

Gene · Ensembl

Fc receptor like 4

Symbol: FCRL4
Biotype: Protein coding
Organism: Homo sapiens
Location: 1:157,573,747-157,598,085
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 9 more facts

HomoloGene ID: 88926
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/83417
genomic end: 157598085
genomic start: 157573747
chromosome: human chromosome 1
cytogenetic location: 1q23.1
expressed in: deltoid muscle
Commons category: FCRL4

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

Fc receptor-like protein 4 is a protein that in humans is encoded by the FCRL4 gene. FCRL4 is an inhibitory receptor expressed on human memory B cells which resides in epithelial tissues.

==References==

Excerpted from Wikipedia’s “FCRL4” article, available under the CC BY-SA 4.0 licence.