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fenbendazole

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Also known as [5-(phenylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester, 5-(phenylthio)-2-benzimidazolecarbamic acid methyl ester, methyl 5-(phenylthio)-2-benzimidazolecarbamate, methyl [5-(phenylthio)-1H-benzimidazol-2-yl]carbamate, Hoe 881v, 2-(methoxycarbonylamino)-5-(phenylthio)benzimidazole

Fenbendazole is a broad-spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: roundworms, hookworms, whipworms, the tapeworm genus Taenia (but not effective against Dipylidium caninum, a common dog tapeworm), pinworms, Aelurostrongylus spp., paragonimiasis, strongyles, and strongyloides that can be administered to sheep, cattle, horses, fish, dogs, cats, rabbits, most reptiles, freshwater shrimp tanks as planaria and hydra treatments, and seals.

Key facts

Drug.S
1
Drug.Verifiedfields
changed
Drug.Watchedfields
changed
Drug.verifiedrevid
443623479
Drug.IUPAC_name
Methyl N-(6-phenylsulfanyl-1H-benzoimidazol-2-yl)carbamate
Drug.image
Fenbendazole.svg
Drug.image_class
skin-invert-image
Drug.DailyMedID
Fenbendazole
Drug.CAS_number
43210-67-9
Drug.ATC_prefix
P02
Drug.ATC_suffix
CA06
Drug.PubChem
3334
Drug.ChemSpiderID
3217
Drug.UNII
621BVT9M36
Drug.KEGG
D04140
Drug.ChEBI
77092
Drug.ChEMBL
37161
Drug.C
15

via Wikipedia infobox

Research

1,520 papers

via PubMed

~5 min read

Encyclopedic overview

12 sections
Contents
  • Mechanism of action
  • Uses in veterinary medicine
  • Dogs and cats
  • Horses
  • Cattle and goats
  • Drug interactions
  • Toxicity
  • Metabolism
  • Safety and precautions
  • Research directions
  • See also
  • References

Fenbendazole is a broad-spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: roundworms, hookworms, whipworms, the tapeworm genus Taenia (but not effective against Dipylidium caninum, a common dog tapeworm), pinworms, Aelurostrongylus spp., paragonimiasis, strongyles, and strongyloides that can be administered to sheep, cattle, horses, fish, dogs, cats, rabbits, most reptiles, freshwater shrimp tanks as planaria and hydra treatments, and seals.

It has not been tested or approved for use in humans by the FDA or EMA. Related benzimidazole drugs such as mebendazole and albendazole are used in humans.

Excerpted from Wikipedia’s “fenbendazole” article, available under the CC BY-SA 4.0 licence.