FERMT2
Sign in to saveAlso known as KIND2, MIG2, PLEKHC1, UNC112, UNC112B, mig-2, fermitin family member 2, URP2SF
Gen der Spezies Homo sapiens
Gene data
FERMT2- Name
- FERM domain containing kindlin 2
- Type
- protein-coding
- Position
- 52,856,943–52,952,435 (−)
- Aliases
- KIND2, MIG2, PLEKHC1, UNC112, UNC112B, mig-2
- Ensembl
- ENSG00000073712
- RefSeq RNA
- NM_001134999.2, NM_001135000.2, NM_006832.3, XM_005267285.4, XM_006720008.4
- RefSeq protein
- NP_001128471.1, NP_001128472.1, NP_006823.1, XP_005267342.1, XP_006720071.1
Enables several functions, including actin binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and type I transforming growth factor beta receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of cell differentiation; and positive regulation of cellular component biogenesis. Acts upstream of or within cell adhesion and protein localization to cell junction. Located in cytosol; focal adhesion; and nucleoplasm. Is extrinsic component of cytoplasmic side of plasma membrane. Part of adherens junction and plasma membrane. Biomarker of acute myeloid leukemia. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
FERM domain containing kindlin 2
- Symbol
- FERMT2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:52,856,943-52,952,435
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 4976
- cytogenetic location
- 14q22.1
- genetic association
- Alzheimer's disease
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10979
- genomic end
- 53419153
- genomic start
- 53323986
- chromosome
- human chromosome 14
via Wikidata · CC0