FGF2

Name

fibroblast growth factor 2

Type

protein-coding

Position

122,826,682–122,898,236 (+)

Aliases

BFGF, FGF-2, FGFB, HBGF-2

Ensembl

ENSG00000138685

RefSeq RNA

NM_001361665.2, NM_002006.6

RefSeq protein

NP_001348594.1, NP_001997.5

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

fibroblast growth factor 2

Symbol

FGF2

Biotype

Protein coding

Organism

Homo sapiens

Location

4:122,826,680-122,898,236

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Image

Protein FGF2 PDB 1bas.png

via Wikidata · CC0