F2RL1

Also known as GPR11, PAR2, Protease activated receptor 2, F2R like trypsin receptor 1

protein-coding gene in the species Homo sapiens

Gene data

F2RL1

Name: F2R like trypsin receptor 1
Type: protein-coding
Aliases: GPR11, PAR2

This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity. [provided by RefSeq, Jun 2016].

via MyGene.info