Structure via PubChem · Public domain (PubChem)
fluoximesterone
Sign in to saveAlso known as Testosterone, 9-fluoro-11beta-hydroxy-17-methyl-, 9alpha-Fluoro-11beta-hydroxy-17-methyltestosterone, 9-Fluoro-11beta,17beta-dihydroxy-17-methylandrost-4-en-3-one, 17alpha-Methyl-9alpha-fluoro-11beta-hydroxytesterone, 11beta,17beta-Dihydroxy-9alpha-fluoro-17alpha-methyl-4-androster-3-one, 17α-Methyl-9α-fluoro-11β-hydroxytesterone, Fluoxymesterone, Fluoxymesteronum
farmaco
Chemical data
- Formula
- C20H29FO3
- Molecular weight
- 336.4 g/mol
- IUPAC name
- (8S,9R,10S,11S,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13,17-trimethyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one
- SMILES
- C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@]2([C@H](C[C@]4([C@H]3CC[C@]4(C)O)C)O)F
- InChIKey
- YLRFCQOZQXIBAB-RBZZARIASA-N
- XLogP
- 2.4
- Polar surface area
- 57.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1956
- Admin. routes
- oral
- Indications
- breast cancer, neoplasm, orchitis, hypogonadism
via ChEMBL · EBI
Research
489 papers- FLUOXYMESTERONE.Journal of the American Medical Association · 1957
- Fluoxymesterone-induced gynaecomastia in a patient with childhood aplastic anaemia.BMJ case reports · 2015
- Fluoxymesterone; a new oral androgen.British medical journal · 1959
- Fluoxymesterone ("halotestin"): a new androgen.The Medical journal of Australia · 1959
- Fluoxymesterone and the development of sexual behavior in the golden hamster.Developmental psychobiology · 1981
via PubMed
Wikidata facts
- Mass
- 336.21
- Has use
- medication
Show 8 more facts
- chemical formula
- C₂₀H₂₉FO₃
- medical condition treated
- hypogonadism
- isomeric SMILES
- C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@]2([C@H](C[C@]4([C@H]3CC[C@]4(C)O)C)O)F
- canonical SMILES
- CC12CCC(=O)C=C1CCC3C2(C(CC4(C3CCC4(C)O)C)O)F
- World Health Organisation international non-proprietary name
- fluoxymesterone
- Commons category
- Fluoxymesterone
- defined daily dose
- 5
- physically interacts with
- androgen receptor
via Wikidata · CC0
Article · Italiano
Il fluoximesterone è uno steroide anabolizzante con forti proprietà androgene, utilizzato nel trattamento di ipogonadismo maschile, ritardo della pubertà nei maschi e nel trattamento del tumore al seno nelle donne.
Abstract from DBpedia / Wikipedia · CC BY-SA