FMO2
Sign in to saveAlso known as FMO1B1, flavin containing monooxygenase 2, flavin containing dimethylaniline monoxygenase 2
Gen der Spezies Homo sapiens
In the Vinony graph
Within Vinony's link graph, FMO2 is referenced by 331 other articles, and connects out to PubMed, Online Mendelian Inheritance in Man and human chromosome 1.
It is catalogued under the topic Genes on human chromosome 1.
Its subject is documented across 5 Wikipedia language editions.
Gene data
FMO2- Name
- flavin containing dimethylaniline monoxygenase 2
- Type
- protein-coding
- Position
- 171,185,249–171,212,686 (+)
- Aliases
- FMO1B1
- Ensembl
- ENSG00000094963
- RefSeq RNA
- NM_001301347.2, NM_001365900.2, NM_001426376.1, NM_001426378.1, NM_001426379.1
- RefSeq protein
- NP_001288276.1, NP_001352829.1, NP_001413305.1, NP_001413307.1, NP_001413308.1
This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
flavin containing dimethylaniline monoxygenase 2
- Symbol
- FMO2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:171,185,249-171,212,686
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 86882
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2327
- chromosome
- human chromosome 1
- genomic start
- 171185249
- genomic end
- 171212686
- cytogenetic location
- 1q24.3
Sources (4)
via Wikidata · CC0