fosfomycin
Also known as Phosphonemycin, Fosfomycinum, Phosphonomycin, 1R-cis-(1,2-Epoxypropyl)phosphonic acid, FCM, (1R,2S)-Epoxypropylphosphonic acid, (-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid, (2R-cis)-(3-Methyloxiranyl)phosphonic acid
Fosfomycin, sold under the brand name Monurol among others, is an antibiotic primarily used to treat lower urinary tract infections. It is not indicated for kidney infections. Occasionally it is used for prostate infections. It is generally taken by mouth.
Key facts
- Drug.Watchedfields
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- 461113563
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- Fosfomycin.svg
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- 125
- Drug.alt
- Structural formula of fosfomycin
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- 150
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- Ball-and-stick model of the fosfomycin molecule
- Drug.tradename
- Monuril, Monurol, Ivozfo, others
- Drug.synonyms
- Phosphomycin, phosphonomycin, fosfomycin tromethamine
Article
10 sectionsContents
- Medical uses
- Bacterial sensitivity
- Resistance
- Side effects
- Mechanism of action
- Immunomodulatory properties
- History
- Biosynthesis
- Synthetic manufacture
- References
Fosfomycin, sold under the brand name Monurol among others, is an antibiotic primarily used to treat lower urinary tract infections. It is not indicated for kidney infections. Occasionally it is used for prostate infections. It is generally taken by mouth.
Common side effects include diarrhea, nausea, headache, and vaginal yeast infections. Severe side effects may include anaphylaxis and Clostridioides difficile-associated diarrhea. While use during pregnancy has not been found to be harmful, such use is not recommended. A single dose when breastfeeding appears safe. Fosfomycin works by interfering with the production of the bacterial cell wall.