Structure via PubChem · Public domain (PubChem)
Fosfomycin
Sign in to saveAlso known as Phosphonemycin, Fosfomycinum, Phosphonomycin, 1R-cis-(1,2-Epoxypropyl)phosphonic acid, FCM, (1R,2S)-Epoxypropylphosphonic acid, (-)-(1R,2S)-(1,2-Epoxypropyl)phosphonic acid, (2R-cis)-(3-Methyloxiranyl)phosphonic acid
Antibiotikum
Key facts
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 461113563
- Drug.image
- Fosfomycin.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 125
- Drug.alt
- Structural formula of fosfomycin
- Drug.image2
- Fosfomycin 3D ball.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 150
- Drug.alt2
- Ball-and-stick model of the fosfomycin molecule
- Drug.tradename
- Monuril, Monurol, Ivozfo, others
- Drug.synonyms
- Phosphomycin, phosphonomycin, fosfomycin tromethamine
- Drug.MedlinePlus
- a697008
- Drug.DailyMedID
- Fosfomycin
- Drug.routes_of_administration
- Intravenous, By mouth
- Drug.ATC_prefix
- J01
- Drug.ATC_suffix
- XX01
- Drug.legal_AU
- S4
via Wikipedia infobox
Chemical data
- Formula
- C3H7O4P
- Molecular weight
- 138.06 g/mol
- IUPAC name
- [(2R,3S)-3-methyloxiran-2-yl]phosphonic acid
- SMILES
- C[C@H]1[C@H](O1)P(=O)(O)O
- InChIKey
- YMDXZJFXQJVXBF-STHAYSLISA-N
- XLogP
- -1.4
- Polar surface area
- 70.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1996
- Admin. routes
- oral
- Indications
- Pseudomonas infection, urinary tract infection, gonorrhea, osteomyelitis
via ChEMBL · EBI
Research
5,297 papers- Fosfomycin Tromethamine: A Urinary Antibiotic.The Journal of the Association of Physicians of India · 2025
- Fosfomycin: 50 Years of A Great Discovery (1969-2019).Archivos espanoles de urologia · 2022
- Fosfomycin for bacterial prostatitis: a review.International journal of antimicrobial agents · 2020
- [Fosfomycin].Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2003
- Mobile fosfomycin resistance genes in Enterobacteriaceae-An increasing threat.MicrobiologyOpen · 2020
via PubMed
Wikidata facts
- Mass
- 138.008
- Has use
- medication
Show 10 more facts
- route of administration
- intravenous infusion and defusion
- Commons category
- Fosfomycin
- subject has role
- antibiotic
- chemical formula
- C₃H₇O₄P
- medical condition treated
- cystitis
- canonical SMILES
- CC1C(O1)P(=O)(O)O
- isomeric SMILES
- C[C@H]1[C@H](O1)P(=O)(O)O
- World Health Organisation international non-proprietary name
- fosfomycin
- different from
- fosmidomycin
- found in taxon
- Streptomyces
Sources (6)
via Wikidata · CC0
Article · Deutsch
Fosfomycin ist ein Arzneistoff (Antibiotikum), der in der Humanmedizin bei schweren bakteriellen Infektionen eingesetzt wird. Fosfomycin wurde 1970 in Alicante (Spanien) aus Streptomyceten isoliert und ist bisher das einzige verfügbare Epoxid-Antibiotikum.
Abstract from DBpedia / Wikipedia · CC BY-SA