FSCN2
Sign in to saveAlso known as RFSN, RP30, fascin actin-bundling protein 2, retinal
Fascin-2 is a protein that in humans is encoded by the FSCN2 gene.
In the Vinony graph
Vinony's link graph records 4 inbound references to FSCN2, and connects out to PubMed, human chromosome 17 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 17.
Vinony links it to 6 Wikipedia language editions.
Gene data
FSCN2- Name
- fascin actin-bundling protein 2, retinal
- Type
- protein-coding
- Position
- 81,528,372–81,542,415 (+)
- Aliases
- RFSN, RP30
- Ensembl
- ENSG00000186765
- RefSeq RNA
- NM_001077182.3, NM_012418.4, XM_011524587.3, XM_011524590.3, XM_047435720.1
- RefSeq protein
- NP_001070650.1, NP_036550.1, XP_011522889.1, XP_011522892.1, XP_047291676.1
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
fascin actin-bundling protein 2, retinal
- Symbol
- FSCN2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:81,528,372-81,542,415
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 22722
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/25794
- chromosome
- human chromosome 17
- genomic start
- 81528377
- genomic end
- 79504156
- cytogenetic location
- 17q25.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Fascin-2 is a protein that in humans is encoded by the FSCN2 gene.
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene.
Excerpted from Wikipedia’s “FSCN2” article, available under the CC BY-SA 4.0 licence.