FSCN2
Sign in to saveAlso known as RFSN, RP30, fascin actin-bundling protein 2, retinal
Fascin-2 is a protein that in humans is encoded by the FSCN2 gene.
Gene data
FSCN2- Name
- fascin actin-bundling protein 2, retinal
- Type
- protein-coding
- Position
- 81,528,377–81,537,130 (+)
- Aliases
- RFSN, RP30
- Ensembl
- ENSG00000186765
- RefSeq RNA
- NM_001077182.3, NM_012418.4, XM_011524587.3, XM_011524590.3, XM_047435720.1
- RefSeq protein
- NP_001070650.1, NP_036550.1, XP_011522889.1, XP_011522892.1, XP_047291676.1
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
fascin actin-bundling protein 2, retinal
- Symbol
- FSCN2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:81,528,372-81,542,415
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 22722
- exact match
- identifiers.org/ncbigene/25794
- genomic start
- 81528377
- genomic end
- 79504156
- cytogenetic location
- 17q25.3
Sources (4)
via Wikidata · CC0
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Article
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- Further reading
- External links
Fascin-2 is a protein that in humans is encoded by the FSCN2 gene.
This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene.