FOSL2
Sign in to saveAlso known as Fos-Related Antigen, FRA-2, FRA2, FOS like 2, AP-1 transcription factor subunit
Fos-related antigen 2 (FRA2) is a protein that in humans is encoded by the FOSL2 gene.
Gene data
FOSL2- Name
- FOS like 2, AP-1 transcription factor subunit
- Type
- protein-coding
- Aliases
- ACED, FRA2
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq, Jul 2014].
via MyGene.info
Gene · Ensembl
FOS like 2, AP-1 transcription factor subunit
- Symbol
- FOSL2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:28,392,448-28,417,317
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 3845
- exact match
- identifiers.org/ncbigene/2355
- genomic end
- 28417317
- genomic start
- 28615315
- cytogenetic location
- 2p23.2
Sources (4)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- See also
- References
- Further reading
- External links
Fos-related antigen 2 (FRA2) is a protein that in humans is encoded by the FOSL2 gene.
== Function == The Fos gene family consists of 4 members: c-Fos, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.