RXRG

Name

retinoid X receptor gamma

Type

protein-coding

Position

165,400,922–165,445,355 (−)

Aliases

NR2B3, RXR-gamma, RXRC, RXRgamma

Ensembl

ENSG00000143171

RefSeq RNA

NM_001256570.2, NM_001256571.2, NM_006917.5, NR_033824.2

RefSeq protein

NP_001243499.1, NP_001243500.1, NP_008848.1

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010].