Structure via PubChem · Public domain (PubChem)
ganciclovir
Sign in to saveAlso known as Vitrasert, GA2, 2-amino-9-((1,3-Dihydroxypropan-2-yloxy)methyl)-3H-purin-6(9H)-one, Ganciclovirum, 2-Amino-9-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1,9-dihydro-purin-6-one, 9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine, 2-amino-9-((1,3-Dihydroxypropan-2-yloxy)methyl)-9H-purin-6-ol, Gancyclovir
Ganciclovir, sold under the brand name Cytovene among others, is an antiviral medication used to treat cytomegalovirus (CMV) infections.
Chemical data
- Formula
- C9H13N5O4
- Molecular weight
- 255.23 g/mol
- IUPAC name
- 2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)-1H-purin-6-one
- SMILES
- C1=NC2=C(N1COC(CO)CO)N=C(NC2=O)N
- InChIKey
- IRSCQMHQWWYFCW-UHFFFAOYSA-N
- XLogP
- -2.5
- Polar surface area
- 135 Ų
- H-bond donors
- 4
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 255.097
- Has use
- medication
Show 10 more facts
- route of administration
- oral administration
- Commons category
- Ganciclovir
- legal status (medicine)
- boxed warning
- chemical formula
- C₉H₁₃N₅O₄
- subject has role
- bactericide
- World Health Organisation international non-proprietary name
- ganciclovir
- medical condition treated
- herpes simplex virus keratitis
- canonical SMILES
- C1=NC2=C(N1COC(CO)CO)NC(=NC2=O)N
- found in taxon
- Acremonium persicinum
- significant drug interaction
- didanosine
Sources (8)
via Wikidata · CC0
~4 min read
Encyclopedic overview
10 sectionsContents
- Medical use
- Veterinary use
- Adverse effects
- Toxicity
- Mechanism of action
- Pharmacokinetics
- Administration
- See also
- References
- Further reading
Ganciclovir, sold under the brand name Cytovene among others, is an antiviral medication used to treat cytomegalovirus (CMV) infections.
Ganciclovir was patented in 1980 and approved for medical use in 1988.
Excerpted from Wikipedia’s “ganciclovir” article, available under the CC BY-SA 4.0 licence.