Also known as GRX, GRX1, glutaredoxin
Glutaredoxin-1 is a protein that in humans is encoded by the GLRX gene.
This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011].
via MyGene.info
Glutaredoxin-1 is a protein that in humans is encoded by the GLRX gene.
==Interactions== GLRX has been shown to interact with Wilson disease protein and ATP7A.
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).