IFIT2
Sign in to saveAlso known as G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K
Interferon-induced protein with tetratricopeptide repeats 2 (commonly termed IFIT2) is a protein that in humans is directed to be produced by the IFIT2 gene. Previously, this gene was termed the G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K, ISG54, or P54 gene and the protein that it directs to be produced was termed the G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K, ISG54, or P54 protein. The IFIT2 gene is one of the many genes that are stimulated by type 1 interferons to form their messenger RNAs and thereby their product proteins. Consequently, the IF
In the Vinony graph
Within Vinony's link graph, IFIT2 is referenced by 7 other articles, and connects out to PubMed, human chromosome 10 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 10.
Its subject is documented across 5 Wikipedia language editions.
Gene data
IFIT2- Name
- interferon induced protein with tetratricopeptide repeats 2
- Type
- protein-coding
- Position
- 89,283,694–89,309,271 (+)
- Aliases
- G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54, ISG-54 K, ISG-54K, ISG54
- Ensembl
- ENSG00000119922
- RefSeq RNA
- NM_001547.5
- RefSeq protein
- NP_001538.4
Enables RNA binding activity. Involved in negative regulation of protein binding activity; positive regulation of apoptotic process; and response to virus. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
interferon induced protein with tetratricopeptide repeats 2
- Symbol
- IFIT2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:89,283,694-89,309,271
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 1187
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3433
- genomic end
- 89309271
- genomic start
- 91061712
- chromosome
- human chromosome 10
- cytogenetic location
- 10q23.31
- expressed in
- spinal ganglia
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Clinical significance
- References
- Further reading
Interferon-induced protein with tetratricopeptide repeats 2 (commonly termed IFIT2) is a protein that in humans is directed to be produced by the IFIT2 gene. Previously, this gene was termed the G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K, ISG54, or P54 gene and the protein that it directs to be produced was termed the G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K, ISG54, or P54 protein. The IFIT2 gene is one of the many genes that are stimulated by type 1 interferons to form their messenger RNAs and thereby their product proteins. Consequently, the IFIT2 gene is classified as one of the many type 1 interferon-stimulated genes.
== Clinical significance ==
Excerpted from Wikipedia’s “IFIT2” article, available under the CC BY-SA 4.0 licence.