Also known as EPG4, PIG8, TP53I8, EI24, autophagy associated transmembrane protein, EI24 autophagy associated transmembrane protein
Etoposide-induced protein 2.4 homolog is a protein that in humans is encoded by the EI24 gene.
This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014].
via MyGene.info
Etoposide-induced protein 2.4 homolog is a protein that in humans is encoded by the EI24 gene.
This gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).