ELF5
Sign in to saveAlso known as ESE2, E74 like ETS transcription factor 5
E74-like factor 5 (ets domain transcription factor), is a gene found in both mice and humans. In humans it is also called ESE2.
Gene data
ELF5- Name
- E74 like ETS transcription factor 5
- Type
- protein-coding
- Aliases
- ESE2
This gene encodes an epithelium-specific ETS family transcription factor. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. This gene has been implicated as a tumor suppressive transcription factor in breast cancer. [provided by RefSeq, May 2022].
via MyGene.info
Gene · Ensembl
E74 like ETS transcription factor 5
- Symbol
- ELF5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:34,478,791-34,525,193
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein ELF5 PDB 1wwx.png
Show 5 more facts
- HomoloGene ID
- 7702
- exact match
- identifiers.org/ncbigene/2001
- genomic end
- 34525193
- genomic start
- 34478791
- cytogenetic location
- 11p13
Sources (4)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Relevance to Disease
- References
- Further reading
- External links
E74-like factor 5 (ets domain transcription factor), is a gene found in both mice and humans. In humans it is also called ESE2.
== Function ==