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GeneQ18027584· pop 5· linked from 5 articles

Also known as CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, P60, RIG-G

Interferon-induced protein with tetratricopeptide repeats 3, also known as interferon-stimulated gene 49 (ISG49), is a protein that in humans is encoded by the IFIT3 gene. It plays a part in the innate immune response to viruses in response to type I interferon signaling.

In the Vinony graph

Within Vinony's link graph, IFIT3 is referenced by 5 other articles, and connects out to PubMed, human chromosome 10 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 10.

Its subject is documented across 5 Wikipedia language editions.

Gene data

IFIT3
Name
interferon induced protein with tetratricopeptide repeats 3
Type
protein-coding
Aliases
CIG-49, GARG-49, IFI60, IFIT4, IRG2, ISG60, P60, RIG-G, cig41

Enables identical protein binding activity. Involved in negative regulation of apoptotic process; negative regulation of cell population proliferation; and response to virus. Located in cytosol and mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

via MyGene.info

Gene · Ensembl

interferon induced protein with tetratricopeptide repeats 3

Symbol
IFIT3
Biotype
Protein coding
Organism
Homo sapiens
Location
10:89,327,307-89,377,473
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 8 more facts
HomoloGene ID
1189
found in taxon
Homo sapiens
genomic end
89377473
genomic start
89327307
cytogenetic location
10q23.31
expressed in
synovial joint
Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • References
  • Further reading

Interferon-induced protein with tetratricopeptide repeats 3, also known as interferon-stimulated gene 49 (ISG49), is a protein that in humans is encoded by the IFIT3 gene. It plays a part in the innate immune response to viruses in response to type I interferon signaling.

== References ==

Excerpted from Wikipedia’s “IFIT3” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0

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