Structure via PubChem · Public domain (PubChem)
iolopride
Sign in to saveAlso known as iodobenzamide, IBZM
Iodobenzamide (IBZM or iolopride) is a pharmaceutical drug used for diagnostic purposes. It is a dopamine antagonist and it can be used by nuclear medicine physicians as a radioactive tracer for SPECT where the radioactive isotope is iodine-123 or iodine-125. The main purpose of a brain study with IBZM is the differentiation of Parkinson's disease from other neurodegenerative diseases such as Lewy Body dementia and multiple system atrophy.
Chemical data
- Formula
- C15H21IN2O3
- Molecular weight
- 404.24 g/mol
- IUPAC name
- N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-hydroxy-3-iodo-6-methoxybenzamide
- SMILES
- CCN1CCC[C@H]1CNC(=O)C2=C(C=CC(=C2O)I)OC
- InChIKey
- CANPFCFJURGKAX-JTQLQIEISA-N
- XLogP
- 2.3
- Polar surface area
- 61.8 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 404.06
Show 4 more facts
- chemical formula
- C₁₅H₂₁IN₂O₃
- isomeric SMILES
- CCN1CCC[C@H]1CNC(=O)C2=C(C=CC(=C2O)I)OC
- canonical SMILES
- CCN1CCCC1CNC(=O)C2=C(C=CC(=C2O)I)OC
- subject has role
- contrast agent
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
2 sectionsContents
- Study
- References
{{Chembox | ImageFile = IBZM.svg | ImageClass = skin-invert-image | PIN = N-{[(2S)-1-Ethylpyrrolidin-2-yl]methyl}-2-hydroxy-3-iodo-6-methoxybenzamide | OtherNames = IBZM; Iolopride |Section1= |Section2= |Section6= |Section7= }}
Iodobenzamide (IBZM or iolopride) is a pharmaceutical drug used for diagnostic purposes. It is a dopamine antagonist and it can be used by nuclear medicine physicians as a radioactive tracer for SPECT where the radioactive isotope is iodine-123 or iodine-125. The main purpose of a brain study with IBZM is the differentiation of Parkinson's disease from other neurodegenerative diseases such as Lewy Body dementia and multiple system atrophy.
Excerpted from Wikipedia’s “iolopride” article, available under the CC BY-SA 4.0 licence.