L-ornithine
Also known as (S)-ornithine, (S)-alpha,delta-diaminovaleric acid, (2S)-2,5-diaminopentanoic acid, L-(-)-Ornithine, (S)-a,D-Diaminovaleric acid, (S)-a,D-Diaminovalerate, (+)-S-Ornithine, 5-Amino-L-Norvaline
Ornithine is a non-proteinogenic α-amino acid that plays a role in the urea cycle. It is not incorporated into proteins during translation. Ornithine is abnormally accumulated in the body in ornithine transcarbamylase deficiency, a disorder of the urea cycle. The moiety derived from ornithine is called ornithyl.
Chemical data
- Formula
- C5H12N2O2
- Molecular weight
- 132.16 g/mol
- IUPAC name
- (2S)-2,5-diaminopentanoate;hydron
- SMILES
- [H+].C(C[C@@H](C(=O)[O-])N)CN
- InChIKey
- AHLPHDHHMVZTML-BYPYZUCNSA-N
- Polar surface area
- 92.2 Ų
- H-bond donors
- 3
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
24,057 papers~3 min read
Article
9 sectionsContents
- Role in urea cycle
- Other reactions
- Research
- Exercise fatigue
- Weightlifting supplement
- Cirrhosis
- See also
- References
- External links
Ornithine is a non-proteinogenic α-amino acid that plays a role in the urea cycle. It is not incorporated into proteins during translation. Ornithine is abnormally accumulated in the body in ornithine transcarbamylase deficiency, a disorder of the urea cycle. The moiety derived from ornithine is called ornithyl.
==Role in urea cycle== L-Ornithine is one of the products of the action of the enzyme arginase on L-arginine, creating urea. Therefore, ornithine is a central component of the urea cycle, which enables the disposal of excess nitrogen. Ornithine itself is recycled and, in a sense, acts as a catalyst.