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lactam
Sign in to savethumb|right|450px|From left to right, the above are general structures of β-lactam, a [[γ-lactam, a δ-lactam, and ε-lactam. Their common names are β-propiolactam, γ-butyrolactam, δ-valerolactam, and ε-caprolactam.]]
Research
178,145 papers- Natural beta-lactam antibiotics.Annual review of microbiology · 1980
- α-Lactam Electrophiles for Covalent Chemical Biology.Angewandte Chemie (International ed. in English) · 2023
- Dihydropyridine Lactam Analogs Targeting BET Bromodomains.ChemMedChem · 2022
- "The Early Beta-Lactam Catches the Germ": Empiric Antimicrobial Sequence in Bloodstream Infections.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
- Intramolecular lactam cross-linking of short oligoureas.Journal of peptide science : an official publication of the European Peptide Society · 2024
via PubMed
Wikidata facts
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- Commons category
- Lactams
- NCI Thesaurus ID
- C0022914
Sources (3)
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~4 min read
Article
12 sectionsContents
- Nomenclature
- Beckmann rearrangement
- Schmidt reaction
- Cyclization of amino acids
- Intramolecular nucleophilic substitution
- Iodolactamization
- Kinugasa reaction
- Diels-Alder reaction
- Lactam–lactim tautomerism
- See also
- References
- External links
thumb|right|450px|From left to right, the above are general structures of β-lactam, a [[γ-lactam, a δ-lactam, and ε-lactam. Their common names are β-propiolactam, γ-butyrolactam, δ-valerolactam, and ε-caprolactam.]]
A lactam is a cyclic amide, formally derived from an amino carboxylic acid through cyclization reactions. The term is a portmanteau of the words lactone + amide.