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uric acid
Sign in to saveAlso known as urate, 2,6,8-Trihydroxypurine, 7,9-dihydro-1H-purine-2,6,8(3H)-trione
end product of nucleic acid degradation
AI overview
Uric acid is a waste product created when your body breaks down nucleic acids, which are the molecules that make up DNA and RNA. Your kidneys filter it out and eliminate it through urine, but when levels get too high in the blood, it can form crystals that cause gout and other health problems.
AI-generated from the Wikipedia summary — may contain errors.
Chemical data
- Formula
- C5H4N4O3
- Molecular weight
- 168.11 g/mol
- IUPAC name
- 7,9-dihydro-3H-purine-2,6,8-trione
- SMILES
- C12=C(NC(=O)N1)NC(=O)NC2=O
- InChIKey
- LEHOTFFKMJEONL-UHFFFAOYSA-N
- XLogP
- -1.9
- Polar surface area
- 99.3 Ų
- H-bond donors
- 4
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
53,676 papers- Uric acid nephrolithiasis: An update.ReviewUrologia · 2018Cicerello EDOI: 10.1177/0391560318766823
- Uric Acid as a Marker of Kidney Disease: Review of the Current Literature.ReviewDisease markers · 2015Giordano C, Karasik O, King-Morris K et al.DOI: 10.1155/2015/382918
- Uric acid calculi.The Journal of urology · 1957ALLYN REDOI: 10.1016/S0022-5347(17)66440-1
- Drugs and uric acid.ReviewAnnual review of pharmacology · 1969Rundles RW, Wyngaarden JBDOI: 10.1146/annurev.pa.09.040169.002021
- Ethanol metabolism and uric acid.ReviewMetabolism: clinical and experimental · 1972Newcombe DSDOI: 10.1016/0026-0495(72)90115-1
- Mechanistic Insights of Soluble Uric Acid-related Kidney Disease.Current medicinal chemistry · 2020Pan J, Shi M, Ma L et al.DOI: 10.2174/0929867326666181211094421
- Role of uric acid in Alzheimer's disease.ReviewJournal of Alzheimer's disease : JAD · 2010Spitsin S, Koprowski HDOI: 10.3233/JAD-2010-1336
- Acute uric acid nephropathy.Archives of internal medicine · 1977Robinson RR, Yarger WE
via PubMed
Wikidata facts
- Mass
- 168.028
- Image
- Fluorescent uric acid.JPG
Show 4 more facts
- Commons category
- Uric acid
- chemical formula
- C₅H₄N₄O₃
- canonical SMILES
- C12=C(NC(=O)N1)NC(=O)NC2=O
- density
- 1.89
Sources (6)
via Wikidata · CC0
~15 min read
Article
Names
Preferred IUPAC name 7,9-Dihydro-1H-purine-2,6,8(3H)-trione
Gallery (5)
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