LAMA1

Also known as LAMA, S-LAM-alpha, PTBHS, Laminin, alpha 1, laminin subunit alpha 1

protein-coding gene in the species Homo sapiens

Gene data

LAMA1

Name: laminin subunit alpha 1
Type: protein-coding
Position: 6,941,742–7,117,859 (−)
Aliases: LAMA, PTBHS, S-LAM-alpha
Ensembl: ENSG00000101680
RefSeq RNA: NM_005559.4
RefSeq protein: NP_005550.2

This gene encodes one of the alpha 1 subunits of laminin. The laminins are a family of extracellular matrix glycoproteins that have a heterotrimeric structure consisting of an alpha, beta and gamma chain. These proteins make up a major component of the basement membrane and have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Mutations in this gene may be associated with Poretti-Boltshauser syndrome. [provided by RefSeq, Sep 2014].