LRPPRC
Sign in to saveAlso known as CLONE-23970, GP130, LRP130, LSFC, leucine rich pentatricopeptide repeat containing, MC4DN5
Leucine-rich PPR motif-containing protein, mitochondrial is a protein that in humans is encoded by the LRPPRC gene. Transcripts ranging in size from 4.8 to 7.0 kb which result from alternative polyadenylation have been reported for this gene.
In the Vinony graph
Vinony's link graph records 8 inbound references to LRPPRC, and connects out to PubMed, human chromosome 2 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 2.
Vinony links it to 5 Wikipedia language editions.
Gene data
LRPPRC- Name
- leucine rich pentatricopeptide repeat containing
- Type
- protein-coding
- Position
- 43,886,224–43,996,226 (−)
- Aliases
- CLONE-23970, GP130, LRP130, LSFC, MC4DN5
- Ensembl
- ENSG00000138095
- RefSeq RNA
- NM_133259.4, XM_006711915.3, XM_006711916.4, XM_047442809.1, XM_054340088.1
- RefSeq protein
- NP_573566.2, XP_006711978.1, XP_006711979.1, XP_047298765.1, XP_054196063.1
This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. [provided by RefSeq, Mar 2012].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
leucine rich pentatricopeptide repeat containing
- Symbol
- LRPPRC
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:43,886,224-43,996,226
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 32695
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10128
- genomic end
- 43996226
- genomic start
- 43886224
- chromosome
- human chromosome 2
- cytogenetic location
- 2p21
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Clinical significance
- References
- Further reading
- External links
Leucine-rich PPR motif-containing protein, mitochondrial is a protein that in humans is encoded by the LRPPRC gene. Transcripts ranging in size from 4.8 to 7.0 kb which result from alternative polyadenylation have been reported for this gene.
==Function== This gene encodes a protein that is leucine-rich and is thought to play a role in regulating the interaction of the cytoskeleton with a variety of cellular processes.
Excerpted from Wikipedia’s “LRPPRC” article, available under the CC BY-SA 4.0 licence.