luliconazole

Also known as Lulicon®, Luzu®, NND-502, PR-2699

Luliconazole, trade names Luzu among others, is an imidazole antifungal medication. As a 1% topical cream, It is indicated for the treatment of athlete's foot, jock itch, and ringworm caused by dermatophytes such as Trichophyton rubrum, Microsporum gypseum, and Epidermophyton floccosum.

In the Vinony graph

Within Vinony's link graph, luliconazole is referenced by 94 other articles, and connects out to antifungal, medication and digital object identifier.

It is catalogued under topics including 1,3-Dithiolanes, Antifungals and Chlorobenzene derivatives.

Its subject is documented across 12 Wikipedia language editions.

Key facts

Drug.IUPAC_name: (2E)-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene](1H-imidazol-1-yl)acetonitrile
Drug.image: Luliconazole.svg
Drug.image_class: skin-invert-image
Drug.image2: Luliconazole ball-and-stick model.png
Drug.image_class2: bg-transparent
Drug.tradename: Luzu, Luzarn, Lulicon, LULY, Zyluli,Luris
Drug.legal_status: Rx-only
Drug.routes_of_administration: Topical
Drug.protein_bound: >99%
Drug.ATC_prefix: D01
Drug.ATC_suffix: AC18
Drug.DrugBank: DB08933
Drug.CAS_number: 187164-19-8
Drug.UNII: RE91AN4S8G
Drug.PubChem: 3003141
Drug.ChemSpiderID: 2273807
Drug.smiles: C1[C@H](S/C(=C(\C#N)/N2C=CN=C2)/S1)C3=C(C=C(C=C3)Cl)Cl
Drug.StdInChI: 1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1

via Wikipedia infobox

Chemical data

Formula: C14H9Cl2N3S2
Molecular weight: 354.3 g/mol
IUPAC name: (2E)-2-[(4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-ylacetonitrile
SMILES: C1[C@H](S/C(=C(\C#N)/N2C=CN=C2)/S1)C3=C(C=C(C=C3)Cl)Cl
InChIKey: YTAOBBFIOAEMLL-REQDGWNSSA-N
XLogP: 4
Polar surface area: 92.2 Å²
H-bond donors: 0
H-bond acceptors: 4
Formal charge: 0