MCUB
Sign in to saveAlso known as EMRE, CCDC109B, Ccdc109b, coiled-coil domain containing 109B, mitochondrial calcium uniporter dominant negative beta subunit, mitochondrial calcium uniporter dominant negative subunit beta
Coiled-coil domain containing 109B (CCDC109B) is a potential calcium uniporter protein found in the membrane of human cells and is encoded by the CCDC109B gene. While CCDC109B is a transmembrane protein it is unclear if it is located within the cell membrane or mitochondrial membrane.
Gene data
MCUB- Name
- mitochondrial calcium uniporter dominant negative subunit beta
- Type
- protein-coding
- Aliases
- CCDC109B
Predicted to enable calcium channel inhibitor activity. Predicted to be involved in calcium import into the mitochondrion and mitochondrial calcium ion homeostasis. Located in mitochondrion and nucleoplasm. Is integral component of mitochondrial inner membrane. Part of uniplex complex. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
Gene · Ensembl
mitochondrial calcium uniporter dominant negative subunit beta
- Symbol
- MCUB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:109,560,209-109,688,799
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 6 more facts
- exact match
- identifiers.org/ncbigene/55013
- HomoloGene ID
- 23056
- genomic end
- 109688719
- genomic start
- 109560209
- cytogenetic location
- 4q25
- Commons category
- Ccdc109b
Sources (4)
via Wikidata · CC0
~8 min read
Article
16 sectionsContents
- Gene information
- Protein information
- Protein domains
- Post-translational modifications
- Phosphorylation sites
- Sumoylation site
- Tertiary structure
- Homology
- Paralog of CCDC109B
- Expression profile
- Role in disease
- Protein-protein interaction
- Transcription factors
- Cellular proteins
- References
- External links
Coiled-coil domain containing 109B (CCDC109B) is a potential calcium uniporter protein found in the membrane of human cells and is encoded by the CCDC109B gene. While CCDC109B is a transmembrane protein it is unclear if it is located within the cell membrane or mitochondrial membrane.
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