Structure via PubChem · Public domain (PubChem)
medifoxamine
Sign in to saveMedifoxamine, previously sold under the brand names Clédial and Gerdaxyl, is an atypical antidepressant with additional anxiolytic properties acting via dopaminergic and serotonergic mechanisms which was formerly marketed in France and Spain, as well as Morocco. The drug was first introduced in France sometime around 1990. It was withdrawn from the market in 1999 (Morocco) and 2000 (France) following incidences of hepatotoxicity.
Chemical data
- Formula
- C16H19NO2
- Molecular weight
- 257.33 g/mol
- IUPAC name
- N,N-dimethyl-2,2-diphenoxyethanamine
- SMILES
- CN(C)CC(OC1=CC=CC=C1)OC2=CC=CC=C2
- InChIKey
- QNMGHBMGNRQPNL-UHFFFAOYSA-N
- XLogP
- 3.8
- Polar surface area
- 21.7 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Indications
- major depressive disorder
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 257.142
Show 3 more facts
- chemical formula
- C₁₆H₁₉NO₂
- canonical SMILES
- CN(C)CC(OC1=CC=CC=C1)OC2=CC=CC=C2
- Commons category
- Medifoxamine
Sources (2)
via Wikidata · CC0
~3 min read
Encyclopedic overview
7 sectionsContents
- Pharmacology
- Pharmacodynamics
- Effectiveness and tolerability
- Society and culture
- Generic names
- Brand names
- References
Medifoxamine, previously sold under the brand names Clédial and Gerdaxyl, is an atypical antidepressant with additional anxiolytic properties acting via dopaminergic and serotonergic mechanisms which was formerly marketed in France and Spain, as well as Morocco. The drug was first introduced in France sometime around 1990. It was withdrawn from the market in 1999 (Morocco) and 2000 (France) following incidences of hepatotoxicity.
==Pharmacology==
Excerpted from Wikipedia’s “medifoxamine” article, available under the CC BY-SA 4.0 licence.