metampicillin
Sign in to saveAlso known as (2S,5R,6R)-3,3-dimethyl-6-[[(2R)-2-(methylideneamino)-2-phenylacetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Metampicillin (INN) is a penicillin antibiotic. It is prepared by the reaction of ampicillin with formaldehyde, and is hydrolysed in aqueous solution with the formation of ampicillin. Hydrolysis is rapid under acid conditions, e.g., in the stomach, less rapid in neutral media, and incomplete in solutions such as human serum.
Research
46 papers- Metampicillin is a cyclic aminal produced by reaction of ampicillin with formaldehyde.Scientific reports · 2020
- [Metampicillin in oral medicine].Lyon medical · 1972
- [Metampicillin in pediatric therapeutics].Annales de pediatrie · 1972
- [Biliary elimination of metampicillin. Experimental and clinical study (author's transl)].Pathologie-biologie · 1976
- [Metampicillin blood levels as a function of the mode of administration of this antibiotic].Bordeaux medical · 1972
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Encyclopedic overview
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Metampicillin (INN) is a penicillin antibiotic. It is prepared by the reaction of ampicillin with formaldehyde, and is hydrolysed in aqueous solution with the formation of ampicillin. Hydrolysis is rapid under acid conditions, e.g., in the stomach, less rapid in neutral media, and incomplete in solutions such as human serum.
==References==
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